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CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation

Neuroblastoma is a tumor arising from pluripotent sympathoadrenal precursor cells of neural cell origin. Neuroblastoma is one of the most aggressive childhood tumors with highly invasive and metastatic potential. The increased expression of urokinase and its receptor is often associated with a negat...

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Detalles Bibliográficos
Autores principales: Rysenkova, Karina D., Semina, Ekaterina V., Karagyaur, Maxim N., Shmakova, Anna A., Dyikanov, Daniyar T., Vasiluev, Petr A., Rubtsov, Yury P., Rubina, Kseniya A., Tkachuk, Vsevolod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047682/
https://www.ncbi.nlm.nih.gov/pubmed/30034627
http://dx.doi.org/10.18632/oncotarget.25647

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