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In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma

While extremely rare in humans, hemangiosarcoma (HSA) accounts for nearly 2% of canine neoplasia, and is characterized by both aggressive local growth/invasion and a high rate of metastasis. Both canine and human HSA exhibit sustained aberrant PI3K/Akt/mTOR pathway signaling. The purpose of this stu...

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Detalles Bibliográficos
Autores principales: Pyuen, Alex A., Meuten, Travis, Rose, Barbara J., Thamm, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047806/
https://www.ncbi.nlm.nih.gov/pubmed/30011343
http://dx.doi.org/10.1371/journal.pone.0200634

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