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In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma
While extremely rare in humans, hemangiosarcoma (HSA) accounts for nearly 2% of canine neoplasia, and is characterized by both aggressive local growth/invasion and a high rate of metastasis. Both canine and human HSA exhibit sustained aberrant PI3K/Akt/mTOR pathway signaling. The purpose of this stu...
Autores principales: | Pyuen, Alex A., Meuten, Travis, Rose, Barbara J., Thamm, Douglas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047806/ https://www.ncbi.nlm.nih.gov/pubmed/30011343 http://dx.doi.org/10.1371/journal.pone.0200634 |
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