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Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease

MicroRNAs (miRNAs) are non-coding RNAs originally involved in RNA silencing and post-transcriptional regulation of gene expression. We have shown in previous work that the miRNA let-7b can act as a signalling molecule for Toll-like receptor 7, thereby initiating innate immune pathways and apoptosis...

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Detalles Bibliográficos
Autores principales: Derkow, Katja, Rössling, Rosa, Schipke, Carola, Krüger, Christina, Bauer, Jakob, Fähling, Michael, Stroux, Andrea, Schott, Eckart, Ruprecht, Klemens, Peters, Oliver, Lehnardt, Seija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047809/
https://www.ncbi.nlm.nih.gov/pubmed/30011310
http://dx.doi.org/10.1371/journal.pone.0200602