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Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing
[Image: see text] Understanding the mechanisms behind amyloid protein aggregation in diseases, such as Parkinson’s and Alzheimer’s disease, is often hampered by the reproducibility of in vitro assays. Yet, understanding the basic mechanisms of protein misfolding is essential for the development of n...
Autores principales: | Stephens, Amberley D., Nespovitaya, Nadezhda, Zacharopoulou, Maria, Kaminski, Clemens F., Phillips, Jonathan J., Kaminski Schierle, Gabriele S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047843/ https://www.ncbi.nlm.nih.gov/pubmed/29750859 http://dx.doi.org/10.1021/acs.analchem.8b01264 |
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