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Sensitive and early detection of mitochondrial dysfunction in the liver of NASH model mice by PET imaging with (18)F-BCPP-BF
BACKGROUND: Nonalcoholic fatty liver disease is a common disorder that progresses from simple fatty liver (steatosis) to nonalcoholic steatohepatitis (NASH). It is thought that mitochondrial dysfunction plays a critical role in the progression of NASH. In this study, we developed a non-invasive meth...
Autores principales: | Sakai, Toshihiro, Ohba, Hiroyuki, Nishiyama, Shingo, Kakiuchi, Takeharu, Inoue, Osamu, Tsukada, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047947/ https://www.ncbi.nlm.nih.gov/pubmed/30014266 http://dx.doi.org/10.1186/s13550-018-0420-6 |
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