Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix

A 67-year-old woman experiencing coughing visited a clinic and was prescribed drugs, including shosaikoto extract, for 4 days. She subsequently suffered from liver injury, but her condition improved after the discontinuation of all medications. Approximately 1 year later, she experienced fatigue, co...

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Detalles Bibliográficos
Autores principales: Shimada, Yutaka, Fujimoto, Makoto, Nogami, Tatsuya, Watari, Hidetoshi, Kitahara, Hideyuki, Misawa, Hiroki, Kimbara, Yoshiyuki, Kita, Kei-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047989/
https://www.ncbi.nlm.nih.gov/pubmed/29434136
http://dx.doi.org/10.2169/internalmedicine.0275-17
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author Shimada, Yutaka
Fujimoto, Makoto
Nogami, Tatsuya
Watari, Hidetoshi
Kitahara, Hideyuki
Misawa, Hiroki
Kimbara, Yoshiyuki
Kita, Kei-ichiro
author_facet Shimada, Yutaka
Fujimoto, Makoto
Nogami, Tatsuya
Watari, Hidetoshi
Kitahara, Hideyuki
Misawa, Hiroki
Kimbara, Yoshiyuki
Kita, Kei-ichiro
author_sort Shimada, Yutaka
collection PubMed
description A 67-year-old woman experiencing coughing visited a clinic and was prescribed drugs, including shosaikoto extract, for 4 days. She subsequently suffered from liver injury, but her condition improved after the discontinuation of all medications. Approximately 1 year later, she experienced fatigue, consulted another clinic, and received saikokeishikankyoto extract for 21 days. She subsequently suffered liver injury again. Both shosaikoto and saikokeishikankyoto contain Scutellariae Radix. This case is thought to be one of recurrent drug-induced liver injury caused by the incidental readministration of a Kampo formula containing Scutellariae Radix. An awareness of adverse drug events caused by Kampo formulas, especially those containing Scutellariae Radix, is essential.
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spelling pubmed-60479892018-07-17 Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix Shimada, Yutaka Fujimoto, Makoto Nogami, Tatsuya Watari, Hidetoshi Kitahara, Hideyuki Misawa, Hiroki Kimbara, Yoshiyuki Kita, Kei-ichiro Intern Med Case Report A 67-year-old woman experiencing coughing visited a clinic and was prescribed drugs, including shosaikoto extract, for 4 days. She subsequently suffered from liver injury, but her condition improved after the discontinuation of all medications. Approximately 1 year later, she experienced fatigue, consulted another clinic, and received saikokeishikankyoto extract for 21 days. She subsequently suffered liver injury again. Both shosaikoto and saikokeishikankyoto contain Scutellariae Radix. This case is thought to be one of recurrent drug-induced liver injury caused by the incidental readministration of a Kampo formula containing Scutellariae Radix. An awareness of adverse drug events caused by Kampo formulas, especially those containing Scutellariae Radix, is essential. The Japanese Society of Internal Medicine 2018-02-09 2018-06-15 /pmc/articles/PMC6047989/ /pubmed/29434136 http://dx.doi.org/10.2169/internalmedicine.0275-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shimada, Yutaka
Fujimoto, Makoto
Nogami, Tatsuya
Watari, Hidetoshi
Kitahara, Hideyuki
Misawa, Hiroki
Kimbara, Yoshiyuki
Kita, Kei-ichiro
Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title_full Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title_fullStr Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title_full_unstemmed Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title_short Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
title_sort recurrent drug-induced liver injury caused by the incidental readministration of a kampo formula containing scutellariae radix
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047989/
https://www.ncbi.nlm.nih.gov/pubmed/29434136
http://dx.doi.org/10.2169/internalmedicine.0275-17
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