Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia

The incidence of Helicobacter pylori-negative gastric cancer is very low. A 60-year-old man was referred to Tokai University Hospital from a local clinic because of eosinophilia. The laboratory data revealed prominent eosinophilia, with a white blood cell count of 7,900 /μL and increased eosinophil...

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Autores principales: Takagi, Atsushi, Ozawa, Hideki, Oki, Masayuki, Yanagi, Hidetaka, Nabeshima, Kazuhito, Nakamura, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047998/
https://www.ncbi.nlm.nih.gov/pubmed/29434119
http://dx.doi.org/10.2169/internalmedicine.0013-17
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author Takagi, Atsushi
Ozawa, Hideki
Oki, Masayuki
Yanagi, Hidetaka
Nabeshima, Kazuhito
Nakamura, Naoya
author_facet Takagi, Atsushi
Ozawa, Hideki
Oki, Masayuki
Yanagi, Hidetaka
Nabeshima, Kazuhito
Nakamura, Naoya
author_sort Takagi, Atsushi
collection PubMed
description The incidence of Helicobacter pylori-negative gastric cancer is very low. A 60-year-old man was referred to Tokai University Hospital from a local clinic because of eosinophilia. The laboratory data revealed prominent eosinophilia, with a white blood cell count of 7,900 /μL and increased eosinophil granulocyte level of 1,659 /μL. After an examination for secondary eosinophilia, esophagogastroduodenoscopy showed an enlarged gastric fold in the corpus, suggesting type 4 gastric cancer. Repeated esophagogastroduodenoscopy (EGD) and a re-biopsy demonstrated poorly differentiated adenocarcinoma and signet ring cell carcinoma. The patient was negative for Helicobacter pylori infection according to the serum anti-Helicobacter pylori antibody, culture and histopathological findings.
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spelling pubmed-60479982018-07-17 Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia Takagi, Atsushi Ozawa, Hideki Oki, Masayuki Yanagi, Hidetaka Nabeshima, Kazuhito Nakamura, Naoya Intern Med Case Report The incidence of Helicobacter pylori-negative gastric cancer is very low. A 60-year-old man was referred to Tokai University Hospital from a local clinic because of eosinophilia. The laboratory data revealed prominent eosinophilia, with a white blood cell count of 7,900 /μL and increased eosinophil granulocyte level of 1,659 /μL. After an examination for secondary eosinophilia, esophagogastroduodenoscopy showed an enlarged gastric fold in the corpus, suggesting type 4 gastric cancer. Repeated esophagogastroduodenoscopy (EGD) and a re-biopsy demonstrated poorly differentiated adenocarcinoma and signet ring cell carcinoma. The patient was negative for Helicobacter pylori infection according to the serum anti-Helicobacter pylori antibody, culture and histopathological findings. The Japanese Society of Internal Medicine 2018-02-09 2018-06-15 /pmc/articles/PMC6047998/ /pubmed/29434119 http://dx.doi.org/10.2169/internalmedicine.0013-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Takagi, Atsushi
Ozawa, Hideki
Oki, Masayuki
Yanagi, Hidetaka
Nabeshima, Kazuhito
Nakamura, Naoya
Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title_full Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title_fullStr Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title_full_unstemmed Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title_short Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia
title_sort helicobacter pylori-negative advanced gastric cancer with massive eosinophilia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047998/
https://www.ncbi.nlm.nih.gov/pubmed/29434119
http://dx.doi.org/10.2169/internalmedicine.0013-17
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