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Tescalcin/c-Src/IGF1Rβ-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1

Tescalcin (TESC; also known as calcineurin B homologous protein 3, CHP3) has recently reported as a regulator of cancer progression. Here, we showed that the elevation of TESC in non-small cell lung cancer (NSCLC) intensifies epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) propert...

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Detalles Bibliográficos
Autores principales:	Lee, Jei Ha, Choi, Soo Im, Kim, Rae Kwon, Cho, Eun Wie, Kim, In Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048049/ https://www.ncbi.nlm.nih.gov/pubmed/30013043 http://dx.doi.org/10.1038/s41598-018-29142-x

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