Non-viral-mediated suppression of AMIGO3 promotes disinhibited NT3-mediated regeneration of spinal cord dorsal column axons

After injury to the mature central nervous system (CNS), myelin-derived inhibitory ligands bind to the Nogo-66 tripartite receptor complex expressed on axonal growth cones, comprised of LINGO-1 and p75(NTR)/TROY and induce growth cone collapse through the RhoA pathway. We have also shown that amphot...

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Detalles Bibliográficos
Autores principales: Almutiri, Sharif, Berry, Martin, Logan, Ann, Ahmed, Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048058/
https://www.ncbi.nlm.nih.gov/pubmed/30013050
http://dx.doi.org/10.1038/s41598-018-29124-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048058/
https://www.ncbi.nlm.nih.gov/pubmed/30013050
http://dx.doi.org/10.1038/s41598-018-29124-z

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