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Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia

BACKGROUND: Leptospirosis is a zoonotic disease that infects human and livestock which causes economic losses to the farmers. It has been reported as one of the causes of reproductive failure in cattle and other ruminants, determining abortions, stillbirth, weak newborns, and decrease in their growt...

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Autores principales: Daud, Aziah, Fuzi, Nik Mohd Hafiz Mohd, Arshad, Mohd Mokhtar, Kamarudin, Suratan, Mohammad, Wan Mohd Zahiruddin Wan, Amran, Fairuz, Ismail, Nabilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048083/
https://www.ncbi.nlm.nih.gov/pubmed/30034179
http://dx.doi.org/10.14202/vetworld.2018.840-844
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author Daud, Aziah
Fuzi, Nik Mohd Hafiz Mohd
Arshad, Mohd Mokhtar
Kamarudin, Suratan
Mohammad, Wan Mohd Zahiruddin Wan
Amran, Fairuz
Ismail, Nabilah
author_facet Daud, Aziah
Fuzi, Nik Mohd Hafiz Mohd
Arshad, Mohd Mokhtar
Kamarudin, Suratan
Mohammad, Wan Mohd Zahiruddin Wan
Amran, Fairuz
Ismail, Nabilah
author_sort Daud, Aziah
collection PubMed
description BACKGROUND: Leptospirosis is a zoonotic disease that infects human and livestock which causes economic losses to the farmers. It has been reported as one of the causes of reproductive failure in cattle and other ruminants, determining abortions, stillbirth, weak newborns, and decrease in their growth rate and milk production. AIM: The objectives of this study were to determine the leptospirosis seroprevalence and to identify the predominant infecting serovars among cattle. MATERIALS AND METHODS: A cross-sectional study involving 420 cattle from six randomly selected districts in Kelantan was conducted. A serological test using the microscopic agglutination test was conducted in the Institute of Medical Research with a cutoff titer for seropositivity of ≥1:100. RESULTS: The overall prevalence of leptospirosis seropositivity among cattle in this study was 81.7% (95% confidence interval: 63.5, 80.1). The most common reaction obtained with the sera tested was from the serovar Sarawak with 78.8%. CONCLUSION: A high seroprevalence of leptospiral antibodies was found among cattle in Northeastern Malaysia. These findings urge that more studies are required to determine the reasons for the high seroprevalence among the cattle along with its transmission and pathogenicity of the local serovar Sarawak.
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spelling pubmed-60480832018-07-20 Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia Daud, Aziah Fuzi, Nik Mohd Hafiz Mohd Arshad, Mohd Mokhtar Kamarudin, Suratan Mohammad, Wan Mohd Zahiruddin Wan Amran, Fairuz Ismail, Nabilah Vet World Research Article BACKGROUND: Leptospirosis is a zoonotic disease that infects human and livestock which causes economic losses to the farmers. It has been reported as one of the causes of reproductive failure in cattle and other ruminants, determining abortions, stillbirth, weak newborns, and decrease in their growth rate and milk production. AIM: The objectives of this study were to determine the leptospirosis seroprevalence and to identify the predominant infecting serovars among cattle. MATERIALS AND METHODS: A cross-sectional study involving 420 cattle from six randomly selected districts in Kelantan was conducted. A serological test using the microscopic agglutination test was conducted in the Institute of Medical Research with a cutoff titer for seropositivity of ≥1:100. RESULTS: The overall prevalence of leptospirosis seropositivity among cattle in this study was 81.7% (95% confidence interval: 63.5, 80.1). The most common reaction obtained with the sera tested was from the serovar Sarawak with 78.8%. CONCLUSION: A high seroprevalence of leptospiral antibodies was found among cattle in Northeastern Malaysia. These findings urge that more studies are required to determine the reasons for the high seroprevalence among the cattle along with its transmission and pathogenicity of the local serovar Sarawak. Veterinary World 2018-06 2018-06-23 /pmc/articles/PMC6048083/ /pubmed/30034179 http://dx.doi.org/10.14202/vetworld.2018.840-844 Text en Copyright: © Daud, et al. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Daud, Aziah
Fuzi, Nik Mohd Hafiz Mohd
Arshad, Mohd Mokhtar
Kamarudin, Suratan
Mohammad, Wan Mohd Zahiruddin Wan
Amran, Fairuz
Ismail, Nabilah
Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title_full Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title_fullStr Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title_full_unstemmed Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title_short Leptospirosis seropositivity and its serovars among cattle in Northeastern Malaysia
title_sort leptospirosis seropositivity and its serovars among cattle in northeastern malaysia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048083/
https://www.ncbi.nlm.nih.gov/pubmed/30034179
http://dx.doi.org/10.14202/vetworld.2018.840-844
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