Interaction of WBP2 with ERα increases doxorubicin resistance of breast cancer cells by modulating MDR1 transcription

BACKGROUND: Surgery combined with new adjuvant chemotherapy is the primary treatment for early stage invasive and advanced stage breast cancer. Growing evidence indicates that patients with ERα-positive breast cancer show poor response to chemotherapeutics. However, ERα-mediated drug-resistant mecha...

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Detalles Bibliográficos
Autores principales: Chen, Shuai, Wang, Han, Li, Zhi, You, Jun, Wu, Qiu-Wan, Zhao, Can, Tzeng, Chi-Meng, Zhang, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048156/
https://www.ncbi.nlm.nih.gov/pubmed/29937544
http://dx.doi.org/10.1038/s41416-018-0119-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048156/
https://www.ncbi.nlm.nih.gov/pubmed/29937544
http://dx.doi.org/10.1038/s41416-018-0119-5

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