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Inhibiting RIPK1 Limits Neuroinflammation and Alleviates Postoperative Cognitive Impairments in D-Galactose-Induced Aged Mice
Neuroinflammation plays a critical role in the pathogenesis of postoperative cognitive dysfunction (POCD) of the elderly patients. Receptor-interacting protein kinase1 (RIPK1) is a key molecular switch modulating inflammation, apoptosis and necroptosis. Here, we investigated whether inhibiting RIPK1...
Autores principales: | Duan, Shangchun, Wang, Xueqin, Chen, Gong, Quan, Chengxuan, Qu, Shuangquan, Tong, Jianbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048190/ https://www.ncbi.nlm.nih.gov/pubmed/30042663 http://dx.doi.org/10.3389/fnbeh.2018.00138 |
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