The Gut Microbiome as a Major Regulator of the Gut-Skin Axis

The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main...

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Detalles Bibliográficos
Autores principales: Salem, Iman, Ramser, Amy, Isham, Nancy, Ghannoum, Mahmoud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/
https://www.ncbi.nlm.nih.gov/pubmed/30042740
http://dx.doi.org/10.3389/fmicb.2018.01459
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author Salem, Iman
Ramser, Amy
Isham, Nancy
Ghannoum, Mahmoud A.
author_facet Salem, Iman
Ramser, Amy
Isham, Nancy
Ghannoum, Mahmoud A.
author_sort Salem, Iman
collection PubMed
description The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions.
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spelling pubmed-60481992018-07-24 The Gut Microbiome as a Major Regulator of the Gut-Skin Axis Salem, Iman Ramser, Amy Isham, Nancy Ghannoum, Mahmoud A. Front Microbiol Microbiology The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions. Frontiers Media S.A. 2018-07-10 /pmc/articles/PMC6048199/ /pubmed/30042740 http://dx.doi.org/10.3389/fmicb.2018.01459 Text en Copyright © 2018 Salem, Ramser, Isham and Ghannoum. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Salem, Iman
Ramser, Amy
Isham, Nancy
Ghannoum, Mahmoud A.
The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_full The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_fullStr The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_full_unstemmed The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_short The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_sort gut microbiome as a major regulator of the gut-skin axis
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/
https://www.ncbi.nlm.nih.gov/pubmed/30042740
http://dx.doi.org/10.3389/fmicb.2018.01459
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