Intestinal Microbiota Disruption Reduces Regulatory T Cells and Increases Respiratory Viral Infection Mortality Through Increased IFNγ Production

Alterations in gastrointestinal microbiota indirectly modulate the risk of atopic disease, but effects on respiratory viral infections are less clear. Using the murine paramyxoviral virus type 1, Sendai virus (SeV), we examined the effect of altering gastrointestinal microbiota on the pulmonary anti...

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Detalles Bibliográficos
Autores principales: Grayson, Mitchell H., Camarda, Lauren E., Hussain, Syed-Rehan A., Zemple, Sarah J., Hayward, Michael, Lam, Vy, Hunter, Desiré A., Santoro, Jennifer L., Rohlfing, Michelle, Cheung, Dorothy S., Salzman, Nita H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048222/
https://www.ncbi.nlm.nih.gov/pubmed/30042764
http://dx.doi.org/10.3389/fimmu.2018.01587

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