Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance

Prions of lower eukaryotes are transmissible protein particles that propagate by converting homotypic soluble proteins into growing protein assemblies. Prion activity is conferred by so-called prion domains, regions of low complexity that are often enriched in glutamines and asparagines (Q/N). The c...

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Detalles Bibliográficos
Autores principales: Duernberger, Yvonne, Liu, Shu, Riemschoss, Katrin, Paulsen, Lydia, Bester, Romina, Kuhn, Peer-Hendrik, Schölling, Manuel, Lichtenthaler, Stefan F., Vorberg, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048315/
https://www.ncbi.nlm.nih.gov/pubmed/29784771
http://dx.doi.org/10.1128/MCB.00111-18

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