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Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death

Glioblastoma (GBM) still carries a poor prognosis due to the refractoriness against antitumor drugs. Temozolomide (TMZ), one of the few standard therapy drugs against GBM worldwide, has only limited effect due to acquired TMZ resistance of GBM. Therefore, development of novel therapeutic methods to...

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Detalles Bibliográficos
Autores principales: YAMAMOTO, Yutaro, SASAKI, Nobuyoshi, KUMAGAI, Kosuke, TAKEUCHI, Satoru, TOYOOKA, Terushige, OTANI, Naoki, WADA, Kojiro, NARITA, Yoshitaka, ICHIMURA, Koichi, NAMBA, Hiroki, MORI, Kentaro, TOMIYAMA, Arata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048351/
https://www.ncbi.nlm.nih.gov/pubmed/29899179
http://dx.doi.org/10.2176/nmc.ra.2018-0040