Cargando…

Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death

Glioblastoma (GBM) still carries a poor prognosis due to the refractoriness against antitumor drugs. Temozolomide (TMZ), one of the few standard therapy drugs against GBM worldwide, has only limited effect due to acquired TMZ resistance of GBM. Therefore, development of novel therapeutic methods to...

Descripción completa

Detalles Bibliográficos
Autores principales:	YAMAMOTO, Yutaro, SASAKI, Nobuyoshi, KUMAGAI, Kosuke, TAKEUCHI, Satoru, TOYOOKA, Terushige, OTANI, Naoki, WADA, Kojiro, NARITA, Yoshitaka, ICHIMURA, Koichi, NAMBA, Hiroki, MORI, Kentaro, TOMIYAMA, Arata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japan Neurosurgical Society 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048351/ https://www.ncbi.nlm.nih.gov/pubmed/29899179 http://dx.doi.org/10.2176/nmc.ra.2018-0040

Ejemplares similares

Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage
por: Kumagai, Kosuke, et al.
Publicado: (2020)

Surgical Strategies for Ruptured Complex Aneurysms Using Skull Base Technique and Revascularization Surgeries
por: Otani, Naoki, et al.
Publicado: (2018)

Modified extradural temporopolar approach with mini-peeling of dura propria for paraclinoid and/or parasellar tumors: Operative technique and nuances
por: Otani, Naoki, et al.
Publicado: (2017)

Usefulness of dural surface tracing of the cortical vessels with indocyanine green videoangiography just prior to dural opening for various cerebrovascular diseases
por: Otani, Naoki, et al.
Publicado: (2017)

Enhanced Malignant Phenotypes of Glioblastoma Cells Surviving NPe6-Mediated Photodynamic Therapy are Regulated via ERK1/2 Activation
por: Kobayashi, Tatsuya, et al.
Publicado: (2020)

Superior Effectiveness of a Newly Developed Nonadherent Polyurethane-Coated Surgical Patty for Hemostasis
por: Otsuka, Yohei, et al.
Publicado: (2021)

Potential Risks and Limited Indications of the Supraorbital Keyhole Approach for Clipping Internal Carotid Artery Aneurysms
por: Toyooka, Terushige, et al.
Publicado: (2019)

Safe fronto-orbito-zygomatic osteotomy using a diamond-coated threadwire saw in orbito-zygomatic craniotomy
por: Wada, Kojiro, et al.
Publicado: (2015)

Horizontal distance of anterior communicating artery aneurysm neck from anterior clinoid process is critically important to predict postoperative complication in clipping via pterional approach
por: Fujii, Takashi, et al.
Publicado: (2017)

Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance
por: Yamamuro, Shun, et al.
Publicado: (2021)

Occipital Interhemispheric Approach for Surgical Removal of the Middle Third Falx Meningioma: Two Case Reports
por: Otani, Naoki, et al.
Publicado: (2018)

Modified extradural temporopolar approach with suction decompression for clipping of large paraclinoid aneurysm: Technical note
por: Otani, Naoki, et al.
Publicado: (2017)

Ruptured Dissecting Aneurysm of the Carotid Artery 12 Years after Gamma Knife Therapy for Pituitary Adenoma
por: Taniguchi, Takahiko, et al.
Publicado: (2020)

Operative surgical nuances of modified extradural temporopolar approach with mini-peeling of dura propria based on cadaveric anatomical study of lateral cavernous structures
por: Otani, Naoki, et al.
Publicado: (2016)

GCT-22. PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT NON-GERMINOMATOUS CNS GERM CELL TUMORS
por: Tomiyama, Arata, et al.
Publicado: (2020)

TB-4 Antitumor effects of a novel curcumin derivative curcumin monoglucuronide on glioblastoma cells in vitro and in vivo
por: Fujii, Takashi, et al.
Publicado: (2021)

ET-02 EFFICACY OF THE SALVAGE THERAPY VIA LOMUSTINE AND NIMUSTINE FOR RECURRENT GLIOBLASTOMA WITH TEMOZOLOMIDE RESISTANCE
por: Yamamuro, Shun, et al.
Publicado: (2019)

Surgical Training for the Management of Intraoperative Aneurysm Rupture Using a Three-Dimensional Artificial Model
por: Kumagai, Kosuke, et al.
Publicado: (2019)

Suction Decompression during Anterior Clinoidectomy for Direct Clipping of Paraclinoid Aneurysm Involving the Anterior Clinoid Process
por: Otani, Naoki, et al.
Publicado: (2018)

ET-09 ACQUIRED MALIGNANT BEHAVIORS OF NPE6-PDT-SURVIVED GLIOBLASTOMA CELLS ARE SUPPRESSED BY USING MEK1/2 INHIBITOR TRAMETINIB
por: Kobayashi, Tatsuya, et al.
Publicado: (2019)

Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years
por: Ohno, Makoto, et al.
Publicado: (2019)

ML-12 MECHANISMS OF CELL DEATH INHIBITION THROUGH CHANGE IN SUBCELLULAR LOCALIZATION OF PIM-1 BY PIM1 GENE MUTATION RECURRENTLY FOUND IN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
por: Sasaki, Nobuyoshi, et al.
Publicado: (2019)

SPDR-06 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORS
por: Tomiyama, Arata, et al.
Publicado: (2019)

CBMS-11 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORS
por: Tomiyama, Arata, et al.
Publicado: (2020)

Protein Phosphatases—A Touchy Enemy in the Battle Against Glioblastomas: A Review
por: Tomiyama, Arata, et al.
Publicado: (2019)

Surgical removal of the solitary metastasis of renal cell carcinoma in the third ventricle using an interhemispheric transcallosal trans-choroidal approach
por: Otani, Naoki, et al.
Publicado: (2015)

Agenesis of the Internal Carotid Artery with Transcavernous Anastomosis Associated with Anterior Communicating Artery Aneurysms
por: Kumagai, Kosuke, et al.
Publicado: (2017)

Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats
por: Takeuchi, Satoru, et al.
Publicado: (2015)

The ALK inhibitors, alectinib and ceritinib, induce ALK‐independent and STAT3‐dependent glioblastoma cell death
por: Kawauchi, Daisuke, et al.
Publicado: (2021)

Chronic Encapsulated Intracerebral Hematoma Associated with Cavernous Malformation
por: Takeuchi, Satoru, et al.
Publicado: (2014)

Anaplastic hemangiopericytoma manifesting as a rapidly enlarging extracranial mass lesion
por: Otani, Naoki, et al.
Publicado: (2012)

Effects of a head-down tilt on cerebral blood flow in mice during bilateral common carotid artery occlusion
por: Nagatani, Kimihiro, et al.
Publicado: (2012)

Eribulin prolongs survival in an orthotopic xenograft mouse model of malignant meningioma
por: Nakano, Tomoyuki, et al.
Publicado: (2021)

Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial
por: Takeuchi, Satoru, et al.
Publicado: (2014)

A Ruptured Aneurysm Located at a Collateral Artery That Extended from the Proximal A2 Segment to the M1 Segment, Associated with an Anomalous Branch of the Anterior Choroidal Artery and Middle Cerebral Artery Hypoplasia: Case Report
por: OTANI, Naoki, et al.
Publicado: (2014)

GCT-46. MULTI-KINASE INHIBITORS AS NOVEL THERAPEUTIC AGENTS AGAINST INTRACRANIAL NON-GERMINOMATOUS GERM CELL TUMORS
por: Uchida, Eita, et al.
Publicado: (2020)

Chronic subdural hematoma associated with moyamoya disease
por: Takeuchi, Satoru, et al.
Publicado: (2014)

Safety of intravenous administration of hydrogen-enriched fluid in patients with acute cerebral ischemia: initial clinical studies
por: Nagatani, Kimihiro, et al.
Publicado: (2013)

Volumetric Analysis of Glioblastoma for Determining Which CpG Sites Should Be Tested by Pyrosequencing to Predict Temozolomide Efficacy
por: Hosoya, Tomohiro, et al.
Publicado: (2022)

Infratentorial arteriovenous malformation associated with persistent primitive hypoglossal artery
por: Kageyama, Hiroshi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uau3reildrb8fbas0m7scb21vl