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Pressure Overload in Mice With Haploinsufficiency of Striated Preferentially Expressed Gene Leads to Decompensated Heart Failure
Striated preferentially expressed gene (Speg) is a member of the myosin light chain kinase family of proteins. Constitutive Speg deficient (Speg(−/−)) mice develop a dilated cardiomyopathy, and the majority of these mice die in utero or shortly after birth. In the present study we assessed the impor...
Autores principales: | Shu, Chang, Huang, He, Xu, Ying, Rota, Marcello, Sorrentino, Andrea, Peng, Yuan, Padera, Robert F., Huntoon, Virginia, Agrawal, Pankaj B., Liu, Xiaoli, Perrella, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048438/ https://www.ncbi.nlm.nih.gov/pubmed/30042693 http://dx.doi.org/10.3389/fphys.2018.00863 |
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