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Germline and somatic variations influence the somatic mutational signatures of esophageal squamous cell carcinomas in a Chinese population

BACKGROUND: Esophageal squamous cell carcinomas (ESCC) is the fourth most lethal cancer in China. Previous studies reveal several highly conserved mutational processes in ESCC. However, it remains unclear what are the true regulators of the mutational processes. RESULTS: We analyzed the somatic muta...

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Detalles Bibliográficos
Autores principales:	Guo, Jintao, Huang, Jiankun, Zhou, Ying, Zhou, Yulin, Yu, Liying, Li, Huili, Hou, Lingyun, Zhu, Liuwei, Ge, Dandan, Zeng, Yuanyuan, Guleng, Bayasi, Li, Qiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048762/ https://www.ncbi.nlm.nih.gov/pubmed/30012096 http://dx.doi.org/10.1186/s12864-018-4906-4

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