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Investigating the Conformation of S100β Protein Under Physiological Parameters Using Computational Modeling: A Clue for Rational Drug Design

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BACKGROUND: Physiochemical factors such as temperature, pH and cofactors are well known parameters that confer conformational changes in a protein structure. With S100β protein being a metal binding brain-specific receptor for both extracellular and intracellular functions, a change in conformation...

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Detalles Bibliográficos
Autores principales:	Tiburu, Elvis K., Issah, Ibrahim, Darko, Mabel, Armah-Sekum, Robert E., Gyampo, Stephen O. A., Amoateng, Nadia K., Kwofie, Samuel K., Awandare, Gordon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2018
Materias:	Biomedical Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048829/ https://www.ncbi.nlm.nih.gov/pubmed/30069254 http://dx.doi.org/10.2174/1874120701812010036

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