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A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336

Background: Preclinical and clinical data suggest that a compound which binds potently to and inhibits the dopamine transporter, but with a slower onset and offset rate than cocaine and with less abuse potential and psychomotor stimulant activity, could be a useful adjunct in the treatment of cocain...

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Detalles Bibliográficos
Autores principales: Carroll, F. Ivy, Kosten, Thomas R., Buda, Jeffrey J., Wang, Laurene, Walters, Bradford B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048956/
https://www.ncbi.nlm.nih.gov/pubmed/30042675
http://dx.doi.org/10.3389/fphar.2018.00712

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