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An Intellectual Disability-Related Missense Mutation in Rac1 Prevents LTP Induction

The small GTPase Rac1 promotes actin polymerization and plays a critical and increasingly appreciated role in the development and plasticity of glutamatergic synapses. Growing evidence suggests that disruption of the Rac1 signaling pathway at glutamatergic synapses contributes to Autism Spectrum Dis...

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Detalles Bibliográficos
Autores principales:	Tian, Chen, Kay, Yuni, Sadybekov, Anastasiia, Rao, Sadhna, Katritch, Vsevolod, Herring, Bruce E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049044/ https://www.ncbi.nlm.nih.gov/pubmed/30042656 http://dx.doi.org/10.3389/fnmol.2018.00223

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