Cargando…

Downregulation and DNA methylation of ECRG4 in gastric cancer

BACKGROUND: Esophageal cancer-related gene 4 (ECRG4) is a novel candidate tumor suppressor gene. Our study investigated the expression and function of ECRG4 in gastric cancer and highlighted the role of DNA hypermethylation at the promoter in silencing the ECRG4 expression. METHODS: The GSE63089 dat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Peng, Chang, Xiao-Jing, Gao, Zi-Ming, Xu, Xiao-Yang, Sun, An-Qi, Li, Kai, Dai, Dong-Qiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049055/ https://www.ncbi.nlm.nih.gov/pubmed/30034241 http://dx.doi.org/10.2147/OTT.S161200

Ejemplares similares

A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma
por: Li, Lin-wei, et al.
Publicado: (2011)

Effect of ECRG2 in combination with cisplatin on the proliferation and apoptosis of EC9706 cells
por: SONG, HAI-YAN, et al.
Publicado: (2014)

ECRG-4 expression in normal and neoplastic choroid plexus
por: Donahue, John E, et al.
Publicado: (2010)

Ecrg4 peptide is the ligand of multiple scavenger receptors
por: Moriguchi, Tetsuo, et al.
Publicado: (2018)

Loss of Ecrg4 improves calcium oxalate nephropathy
por: Cabuzu, Daniela, et al.
Publicado: (2022)

AB244. Down-regulated ECRG4 is associated with poor prognosis in renal cell cancer and is regulated by promoter DNA methylation
por: Li, Zesong, et al.
Publicado: (2016)

Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion
por: Li, Wei, et al.
Publicado: (2010)

ECRG4 inhibits growth and invasiveness of squamous cell carcinoma of the head and neck in vitro and in vivo
por: XU, TING, et al.
Publicado: (2013)

ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer
por: Rose, Michael, et al.
Publicado: (2020)

Ecrg4 Attenuates the Inflammatory Proliferative Response of Mucosal Epithelial Cells to Infection
por: Kurabi, Arwa, et al.
Publicado: (2013)

ECRG4 Expression in Normal Rat Tissues: Expression Study and Literature Review
por: Porzionato, A., et al.
Publicado: (2015)

A potential link between aberrant expression of ECRG4 and atrial fibrillation
por: Zhang, Zuojing, et al.
Publicado: (2023)

ECRG4 acts as a tumor suppressor gene frequently hypermethylated in human breast cancer
por: Tang, Gao-Yan, et al.
Publicado: (2019)

Down-Regulation of ECRG4, a Candidate Tumor Suppressor Gene, in Human Breast Cancer
por: Sabatier, Renaud, et al.
Publicado: (2011)

ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
por: Götze, Silke, et al.
Publicado: (2009)

ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury
por: Dorschner, Robert A., et al.
Publicado: (2020)

MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation
por: Li, Yong-Shuang, et al.
Publicado: (2019)

A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms
por: JIA, JIANPING, et al.
Publicado: (2015)

ECRG2, a novel transcriptional target of p53, modulates cancer cell sensitivity to DNA damage
por: Patel, Harsh, et al.
Publicado: (2020)

Correction to "MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation"
por: Li, Yong-Shuang, et al.
Publicado: (2022)

The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma
por: Li, Linwei, et al.
Publicado: (2010)

ECRG2 enhances the anti-cancer effects of cisplatin in cisplatin-resistant esophageal cancer cells via upregulation of p53 and downregulation of PCNA
por: Hou, Xin-Fang, et al.
Publicado: (2017)

The ECRG4 cleavage product augurin binds the endotoxin receptor and influences the innate immune response during otitis media
por: Kurabi, Arwa, et al.
Publicado: (2022)

ECRG4 Represses Cell Proliferation and Invasiveness via NFIC/OGN/NF-κB Signaling Pathway in Bladder Cancer
por: Liang, Xin, et al.
Publicado: (2020)

Retraction: The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma
por: Li, Linwei, et al.
Publicado: (2011)

Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4
por: Xia, Zhiwei, et al.
Publicado: (2018)

Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4
por: Xia, Zhiwei, et al.
Publicado: (2021)

Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance
por: Chen, Jing, et al.
Publicado: (2016)

Downregulation of promoter methylation gene PRDM5 contributes to the development of tumor proliferation and predicts poor prognosis in gastric cancer
por: Teng, Jing-jing, et al.
Publicado: (2021)

DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer
por: Meng, Qi, et al.
Publicado: (2021)

Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury
por: Gonzalez, Ana Maria, et al.
Publicado: (2011)

Methyl 2-{[(2-furyl)(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)methyl]amino}acetate
por: Han, Xiao, et al.
Publicado: (2011)

Downregulation of STARD8 in gastric cancer and its involvement in gastric cancer progression
por: Zhang, Shuanglong, et al.
Publicado: (2018)

DNA methylation signatures associated with prognosis of gastric cancer
por: Dai, Jin, et al.
Publicado: (2021)

Aberrant DNA Methylation-Mediated FOXF2 Dysregulation Is a Prognostic Risk Factor for Gastric Cancer
por: Zhang, Cheng, et al.
Publicado: (2021)

Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer
por: CHEN, JING, et al.
Publicado: (2015)

Predictive value of DNA methylation in the efficacy of chemotherapy for gastric cancer
por: Li, Ye, et al.
Publicado: (2023)

Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia
por: Li, Chenxi, et al.
Publicado: (2022)

PBX1 attributes as a determinant of connexin 32 downregulation in Helicobacter pylori-related gastric carcinogenesis
por: Liu, Xiao-Ming, et al.
Publicado: (2017)

Aberrant methylation of secreted protein acidic and rich in cysteine gene and its significance in gastric cancer
por: Shao, Shuai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_eqfeh8li78ahdd0utcdg32it41