The miR-200 family: multiple effects on gliomas

Gliomas are the most common type of primary brain tumors. MicroRNAs (miRNAs) are small noncoding RNAs that can epigenetically regulate target gene expression. The microRNA 200 family includes miR-200a, 200b, 200c, 141 and 429. Numerous studies have indicated that members of the miR-200 family play a...

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Detalles Bibliográficos
Autores principales: Peng, Lilei, Fu, Jie, Ming, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049059/
https://www.ncbi.nlm.nih.gov/pubmed/30034253
http://dx.doi.org/10.2147/CMAR.S160945
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author Peng, Lilei
Fu, Jie
Ming, Yang
author_facet Peng, Lilei
Fu, Jie
Ming, Yang
author_sort Peng, Lilei
collection PubMed
description Gliomas are the most common type of primary brain tumors. MicroRNAs (miRNAs) are small noncoding RNAs that can epigenetically regulate target gene expression. The microRNA 200 family includes miR-200a, 200b, 200c, 141 and 429. Numerous studies have indicated that members of the miR-200 family play an important role in glioma development and metastasis. In this review, we summarize the data from various studies and highlight the effects of miR-200 on glioma metastasis, therapeutic response and prognosis.
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spelling pubmed-60490592018-07-20 The miR-200 family: multiple effects on gliomas Peng, Lilei Fu, Jie Ming, Yang Cancer Manag Res Review Gliomas are the most common type of primary brain tumors. MicroRNAs (miRNAs) are small noncoding RNAs that can epigenetically regulate target gene expression. The microRNA 200 family includes miR-200a, 200b, 200c, 141 and 429. Numerous studies have indicated that members of the miR-200 family play an important role in glioma development and metastasis. In this review, we summarize the data from various studies and highlight the effects of miR-200 on glioma metastasis, therapeutic response and prognosis. Dove Medical Press 2018-07-13 /pmc/articles/PMC6049059/ /pubmed/30034253 http://dx.doi.org/10.2147/CMAR.S160945 Text en © 2018 Peng et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Peng, Lilei
Fu, Jie
Ming, Yang
The miR-200 family: multiple effects on gliomas
title The miR-200 family: multiple effects on gliomas
title_full The miR-200 family: multiple effects on gliomas
title_fullStr The miR-200 family: multiple effects on gliomas
title_full_unstemmed The miR-200 family: multiple effects on gliomas
title_short The miR-200 family: multiple effects on gliomas
title_sort mir-200 family: multiple effects on gliomas
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049059/
https://www.ncbi.nlm.nih.gov/pubmed/30034253
http://dx.doi.org/10.2147/CMAR.S160945
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