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Impaired DNA demethylation of C/EBP sites causes premature aging

Changes in DNA methylation are among the best-documented epigenetic alterations accompanying organismal aging. However, whether and how altered DNA methylation is causally involved in aging have remained elusive. GADD45α (growth arrest and DNA damage protein 45A) and ING1 (inhibitor of growth family...

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Detalles Bibliográficos
Autores principales:	Schäfer, Andrea, Mekker, Bernadette, Mallick, Medhavi, Vastolo, Viviana, Karaulanov, Emil, Sebastian, Dominik, von der Lippen, Carina, Epe, Bernd, Downes, Damien J., Scholz, Carola, Niehrs, Christof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513/ https://www.ncbi.nlm.nih.gov/pubmed/29884649 http://dx.doi.org/10.1101/gad.311969.118

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