PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia

Proper organization and orderly mitosis of radial glial progenitors (RGPs) drive the formation of a laminated mammalian cortex in the correct size. However, the molecular underpinnings of the intricate process remain largely unclear. Here we show that RGP behavior and cortical development are contro...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wenying Angela, Chen, She, Li, Zhizhong, Lee, Choong Heon, Mirzaa, Ghayda, Dobyns, William B., Ross, M. Elizabeth, Zhang, Jiangyang, Shi, Song-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049519/
https://www.ncbi.nlm.nih.gov/pubmed/29899142
http://dx.doi.org/10.1101/gad.313171.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049519/
https://www.ncbi.nlm.nih.gov/pubmed/29899142
http://dx.doi.org/10.1101/gad.313171.118

Ejemplares similares