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Design and synthesis of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives bearing a hydrazone moiety as potential fungicides

BACKGROUND: Tetramic acid, thiophene and hydrazone derivatives were found to exhibit favorable antifungal activity. Aiming to discover novel template molecules with potent antifungal activity, a series of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives containing a hydrazone group we...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobin, Ren, Zhengjiao, Wang, Mengqi, Chen, Min, Lu, Aiming, Si, Weijie, Yang, Chunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049848/
https://www.ncbi.nlm.nih.gov/pubmed/30019094
http://dx.doi.org/10.1186/s13065-018-0452-z