A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers

Non-small cell lung cancers (NSCLC) account for 85% of all lung cancers, and the epidermal growth factor receptor (EGFR) is highly expressed or activated in many NSCLC that permit use of EGFR tyrosine kinase inhibitors (TKIs) as frontline therapies. Resistance to EGFR TKIs eventually develops that n...

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Detalles Bibliográficos
Autores principales: Cheriyan, Vino T., Alsaab, Hashem, Sekhar, Sreeja, Venkatesh, Jaganathan, Mondal, Arindam, Vhora, Imran, Sau, Samaresh, Muthu, Magesh, Polin, Lisa A., Levi, Edi, Bepler, Gerold, Iyer, Arun K., Singh, Mandip, Rishi, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049854/
https://www.ncbi.nlm.nih.gov/pubmed/30038713
http://dx.doi.org/10.18632/oncotarget.25671

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