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Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus
Endonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related to mobile genetic elements. They share a structurally defined catalytic domain for site-specific nicking and strand-transfer reactions, which...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049929/ https://www.ncbi.nlm.nih.gov/pubmed/30016371 http://dx.doi.org/10.1371/journal.pone.0200841 |