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Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus

Endonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related to mobile genetic elements. They share a structurally defined catalytic domain for site-specific nicking and strand-transfer reactions, which...

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Detalles Bibliográficos
Autores principales: Agúndez, Leticia, Zárate-Pérez, Francisco, Meier, Anita F., Bardelli, Martino, Llosa, Matxalen, Escalante, Carlos R., Linden, R. Michael, Henckaerts, Els
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049929/
https://www.ncbi.nlm.nih.gov/pubmed/30016371
http://dx.doi.org/10.1371/journal.pone.0200841