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Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation

Glucosamine (GlcN) is a naturally occurring derivative of glucose and an over-the-counter food additive. However, the mechanism underlying GlcN action on cells is unknown. In this study, we investigated the effect of GlcN on natural killer (NK) cells. We demonstrate that GlcN affects NK-92 cell cyto...

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Detalles Bibliográficos
Autores principales: Božič, Janja, Stoka, Veronika, Dolenc, Iztok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049946/
https://www.ncbi.nlm.nih.gov/pubmed/30016365
http://dx.doi.org/10.1371/journal.pone.0200757