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COBRAme: A computational framework for genome-scale models of metabolism and gene expression

Genome-scale models of metabolism and macromolecular expression (ME-models) explicitly compute the optimal proteome composition of a growing cell. ME-models expand upon the well-established genome-scale models of metabolism (M-models), and they enable a new fundamental understanding of cellular grow...

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Detalles Bibliográficos
Autores principales:	Lloyd, Colton J., Ebrahim, Ali, Yang, Laurence, King, Zachary A., Catoiu, Edward, O’Brien, Edward J., Liu, Joanne K., Palsson, Bernhard O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049947/ https://www.ncbi.nlm.nih.gov/pubmed/29975681 http://dx.doi.org/10.1371/journal.pcbi.1006302

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