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Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells

PURPOSE: To investigate the impact of ascorbate, via DNA hydroxymethylation, on VEGF expression in retinal pigment epithelial (RPE) cells. METHODS: Dot-blot and hydroxymethylated DNA immunoprecipitation sequencing were applied to evaluate the impact of ascorbate on DNA hydroxymethylation in ARPE-19...

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Detalles Bibliográficos
Autores principales:	Sant, David W., Camarena, Vladimir, Mustafi, Sushmita, Li, Yiwen, Wilkes, Zachary, Van Booven, Derek, Wen, Rong, Wang, Gaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049987/ https://www.ncbi.nlm.nih.gov/pubmed/30025088 http://dx.doi.org/10.1167/iovs.18-24101

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