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High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug

We highlight the absence of high-level evidence from dose-ranging studies regarding the use of oral ivermectin in susceptible parasitic diseases. We provide published data supporting the use of a higher dosage regimen of ivermectin in malaria and difficult-to-treat head lice, and announce an ongoing...

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Detalles Bibliográficos
Autores principales: Chosidow, Olivier, Bernigaud, Charlotte, Do-Pham, Giao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050034/
https://www.ncbi.nlm.nih.gov/pubmed/30016258
http://dx.doi.org/10.1051/parasite/2018039
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author Chosidow, Olivier
Bernigaud, Charlotte
Do-Pham, Giao
author_facet Chosidow, Olivier
Bernigaud, Charlotte
Do-Pham, Giao
author_sort Chosidow, Olivier
collection PubMed
description We highlight the absence of high-level evidence from dose-ranging studies regarding the use of oral ivermectin in susceptible parasitic diseases. We provide published data supporting the use of a higher dosage regimen of ivermectin in malaria and difficult-to-treat head lice, and announce an ongoing randomized clinical trial in severe scabies.
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spelling pubmed-60500342018-08-01 High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug Chosidow, Olivier Bernigaud, Charlotte Do-Pham, Giao Parasite Short Note We highlight the absence of high-level evidence from dose-ranging studies regarding the use of oral ivermectin in susceptible parasitic diseases. We provide published data supporting the use of a higher dosage regimen of ivermectin in malaria and difficult-to-treat head lice, and announce an ongoing randomized clinical trial in severe scabies. EDP Sciences 2018-07-16 /pmc/articles/PMC6050034/ /pubmed/30016258 http://dx.doi.org/10.1051/parasite/2018039 Text en © O. Chosidow et al., published by EDP Sciences, 2018 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Note
Chosidow, Olivier
Bernigaud, Charlotte
Do-Pham, Giao
High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title_full High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title_fullStr High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title_full_unstemmed High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title_short High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
title_sort high-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug
topic Short Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050034/
https://www.ncbi.nlm.nih.gov/pubmed/30016258
http://dx.doi.org/10.1051/parasite/2018039
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