A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling

Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially modulated are unknown. Here we show that the pos...

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Detalles Bibliográficos
Autores principales: Parvatiyar, Kislay, Pindado, Jose, Dev, Anurupa, Aliyari, Saba Roghiyh, Zaver, Shivam A., Gerami, Hoda, Chapon, Maxime, Ghaffari, Amir A., Dhingra, Anant, Cheng, Genhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050272/
https://www.ncbi.nlm.nih.gov/pubmed/30018345
http://dx.doi.org/10.1038/s41467-018-05168-7

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