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P31–43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease

Celiac disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins. Some gliadin peptides are resistant to intestinal digestion (e.g., A-gliadin P31–43) and induce a stress/innate immune response, but the reason why they ar...

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Detalles Bibliográficos
Autores principales: Nanayakkara, Merlin, Lania, Giuliana, Maglio, Mariantonia, Auricchio, Renata, De Musis, Cristiana, Discepolo, Valentina, Miele, Erasmo, Jabri, Bana, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050301/
https://www.ncbi.nlm.nih.gov/pubmed/30018339
http://dx.doi.org/10.1038/s41598-018-28830-y