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The membrane-associated fraction of cyclase associate protein 1 translocates to the cytosol upon platelet stimulation

Platelets undergo profound shape changes upon adhesion to damaged blood vessel walls that are mediated by reorganisation of the actin cytoskeleton in response to receptor-mediated signalling cascades. The highly conserved 56 kDa multidomain cyclase associated protein 1 (CAP1) works in concert with c...

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Detalles Bibliográficos
Autores principales: Joshi, Pooja, Riley, David R. J., Khalil, Jawad S., Xiong, Huajiang, Ji, Wei, Rivero, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050311/
https://www.ncbi.nlm.nih.gov/pubmed/30018317
http://dx.doi.org/10.1038/s41598-018-29151-w