Globular-shaped variable lymphocyte receptors B antibody multimerized by a hydrophobic clustering in hagfish

In hagfish and lampreys, two representative jawless vertebrates, the humoral immunity is directly mediated by variable lymphocyte receptors B (VLRBs). Both monomeric VLRBs are structurally and functionally similar, but their C-terminal tails differ: lamprey VLRB has a Cys-rich tail that forms disulf...

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Detalles Bibliográficos
Autores principales: Kim, Jaesung, Im, Se Pyeong, Lee, Jung Seok, Lazarte, Jassy Mary S., Kim, Si Won, Jung, Jae Wook, Kim, Jong Yong, Kim, Young Rim, Lee, Sangmin, Kim, Gwang Joong, Jung, Hyun Suk, Lee, Kyun Oh, Adams, Alexandra, Thompson, Kim D., Jung, Tae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050320/
https://www.ncbi.nlm.nih.gov/pubmed/30018426
http://dx.doi.org/10.1038/s41598-018-29197-w

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