Cargando…

Plasmatic Levels of IL-18, IP-10, and Activated CD8(+) T Cells Are Potential Biomarkers to Identify HIV-1 Elite Controllers With a True Functional Cure Profile

Elite controllers (ECs) are rare individuals able to naturally control HIV-1 replication below the detection limit of viral load (VL) commercial assays. It is unclear, however, whether ECs might be considered a natural model of a functional cure because some studies have noted CD4(+) T cell depletio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Côrtes, Fernanda H., de Paula, Hury H. S., Bello, Gonzalo, Ribeiro-Alves, Marcelo, de Azevedo, Suwellen S. D., Caetano, Diogo G., Teixeira, Sylvia L. M., Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea G., Guimarães, Monick L., Morgado, Mariza G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050358/ https://www.ncbi.nlm.nih.gov/pubmed/30050532 http://dx.doi.org/10.3389/fimmu.2018.01576

Ejemplares similares

HIV-1 elite controllers present a high frequency of activated regulatory T and Th17 cells
por: Caetano, Diogo G., et al.
Publicado: (2020)

Ongoing HIV-1 evolution and reservoir reseeding in two elite controllers with genetically diverse peripheral proviral quasispecies
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2023)

Proviral Quasispecies Diversity Is Not Associated With Virologic Breakthrough or CD4(+) T Cell Loss in HIV-1 Elite Controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2019)

A case report of HIV-1 superinfection in an HIV controller leading to loss of viremia control: a retrospective of 10 years of follow-up
por: Caetano, Diogo Gama, et al.
Publicado: (2019)

Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2017)

Comparative HIV-1 Proviral Dynamics in Two Individuals That Maintained Viral Replication Control with or without Antiretroviral Therapy following Superinfection
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control
por: Caetano, Diogo Gama, et al.
Publicado: (2018)

Increased biomarkers of cardiovascular risk in HIV-1 viremic controllers and low persistent inflammation in elite controllers and art-suppressed individuals
por: Caetano, Diogo Gama, et al.
Publicado: (2022)

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2020)

Reduction of inflammation and T cell activation after 6 months of cART initiation during acute, but not in early chronic HIV-1 infection
por: de Paula, Hury Hellen Souza, et al.
Publicado: (2018)

HIV-1 Diversity and Drug Resistance in Treatment-Naïve Children and Adolescents from Rio de Janeiro, Brazil
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Prevalence, estimated HIV-1 incidence and viral diversity among people seeking voluntary counseling and testing services in Rio de Janeiro, Brazil
por: de Castro, Carlos A Velasco, et al.
Publicado: (2010)

HIV-1 Diversity and Drug Resistance Mutations among People Seeking HIV Diagnosis in Voluntary Counseling and Testing Sites in Rio de Janeiro, Brazil
por: Velasco-de-Castro, Carlos A., et al.
Publicado: (2014)

Reduction of HIV-1 Reservoir Size and Diversity After 1 Year of cART Among Brazilian Individuals Starting Treatment During Early Stages of Acute Infection
por: Leite, Thaysse Ferreira, et al.
Publicado: (2019)

Transmitted drug resistance in patients with acute/recent HIV infection in Brazil
por: Ferreira, Ana Cristina G., et al.
Publicado: (2017)

HIV-1 Genetic Diversity and Transmitted Drug Resistance Mutations among Patients from the North, Central and South Regions of Angola
por: Afonso, Joana Morais, et al.
Publicado: (2012)

Association of Single Nucleotide Polymorphisms in the Lens Epithelium-Derived Growth Factor (LEDGF/p75) with HIV-1 Infection Outcomes in Brazilian HIV-1+ Individuals
por: Passaes, Caroline Pereira Bittencourt, et al.
Publicado: (2014)

Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal
por: de Pina-Araujo, Isabel Inês M., et al.
Publicado: (2015)

Telemedicine as a tool for PrEP delivery during the COVID-19 pandemic in a large HIV prevention service in Rio de Janeiro-Brazil
por: Hoagland, Brenda, et al.
Publicado: (2020)

High acceptability of PrEP teleconsultation and HIV self-testing among PrEP users during the COVID-19 pandemic in Brazil
por: Hoagland, Brenda, et al.
Publicado: (2020)

Cross-Neutralizing Antibodies in HIV-1 Individuals Infected by Subtypes B, F1, C or the B/Bbr Variant in Relation to the Genetics and Biochemical Characteristics of the env Gene
por: de Almeida, Dalziza Victalina, et al.
Publicado: (2016)

Profile of the HIV Epidemic in Cape Verde: Molecular Epidemiology and Drug Resistance Mutations among HIV-1 and HIV-2 Infected Patients from Distinct Islands of the Archipelago
por: de Pina-Araujo, Isabel Inês M., et al.
Publicado: (2014)

Pre-exposure prophylaxis for men and transgender women who have sex with men in Brazil: opportunities and challenges
por: Veloso, Valdilea G, et al.
Publicado: (2015)

The HIV-1 epidemic in Bolivia is dominated by subtype B and CRF12_BF "family" strains
por: Guimarães, Monick L, et al.
Publicado: (2012)

The HIV epidemic in Latin America: accomplishments and challenges on treatment and prevention
por: Luz, Paula M., et al.
Publicado: (2019)

Pre-exposure prophylaxis use, HIV knowledge, and internalized homonegativity among men who have sex with men in Brazil: A cross-sectional study
por: Blair, Kevin J., et al.
Publicado: (2021)

Moderating Effect of Pre-Exposure Prophylaxis Use on the Association Between Sexual Risk Behavior and Perceived Risk of HIV Among Brazilian Gay, Bisexual, and Other Men Who Have Sex With Men: Cross-Sectional Study
por: Blair, Kevin James, et al.
Publicado: (2023)

Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil
por: Marques, Bianca Cristina Leires, et al.
Publicado: (2018)

Alterations in postmenopausal plasmatic lipidome
por: Nogueira, Iara Antonia Lustosa, et al.
Publicado: (2018)

Temporal dynamics of HIV-1 circulating subtypes in distinct exposure categories in southern Brazil
por: Almeida, Sabrina EM, et al.
Publicado: (2012)

Evaluation of the plasmatic level of mepivacaine in different anatomical regions
por: Ferreira, Jéssica-Caroline-Afonso, et al.
Publicado: (2018)

Awareness of Prevention Strategies and Willingness to Use Preexposure Prophylaxis in Brazilian Men Who Have Sex With Men Using Apps for Sexual Encounters: Online Cross-Sectional Study
por: Torres, Thiago Silva, et al.
Publicado: (2018)

Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography
por: Perazzo, Hugo, et al.
Publicado: (2015)

Chronic Hepatitis C: An Overview of Evidence on Epidemiology and Management from a Brazilian Perspective
por: Castro, Rodolfo, et al.
Publicado: (2015)

Towards an ideal antiretroviral regimen for the global HIV epidemic
por: Grinsztejn, Beatriz, et al.
Publicado: (2017)

Identification of a new circulating recombinant form of human immunodeficiency virus type 1, CRF124_cpx involving subtypes A, G, H, and CRF27_cpx in Angola
por: Da Silva, Rayana Katylin Mendes, et al.
Publicado: (2022)

RECAP reveals the true statistical significance of ChIP-seq peak calls
por: Chitpin, Justin G, et al.
Publicado: (2019)

Impact of COVID-19 Pandemic on Sexual Minority Populations in Brazil: An Analysis of Social/Racial Disparities in Maintaining Social Distancing and a Description of Sexual Behavior
por: Torres, Thiago S., et al.
Publicado: (2020)

Plasmatic markers in hemorrhagic stroke
por: Marginean, IC, et al.
Publicado: (2011)

Production of Plasmatic Cell Juices—Experiments in Immunization and Clinical Treatment with the Plasmatic Cell Juices of Bacteria
Publicado: (1898)

Cannot write session to /tmp/vufind_sessions/sess_7u4ij9ou094r5hp9rsfthe9dhm