Cortical Axonal Secretion of BDNF in the Striatum Is Disrupted in the Mutant-huntingtin Knock-in Mouse Model of Huntington's Disease

Deficient BDNF signaling is known to be involved in neurodegenerative diseases such as Huntington's disease (HD). Mutant huntingtin (mhtt)-mediated disruption of either BDNF transcription or transport is thought to be a factor contributing to striatal atrophy in the HD brain. Whether and how ac...

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Detalles Bibliográficos
Autor principal: Park, Hyungju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050413/
https://www.ncbi.nlm.nih.gov/pubmed/30022873
http://dx.doi.org/10.5607/en.2018.27.3.217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050413/
https://www.ncbi.nlm.nih.gov/pubmed/30022873
http://dx.doi.org/10.5607/en.2018.27.3.217

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