Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing

Tamoxifen (Nolvadex) is one of the most widely used and effective therapeutic agent for breast cancer. It benefits nearly 75% of patients with estrogen receptor (ER)-positive breast cancer that receive this drug. Its effectiveness is mainly attributed to its capacity to function as an ER antagonist,...

Descripción completa

Detalles Bibliográficos
Autores principales: Rouhimoghadam, Milad, Safarian, Shahrokh, Carroll, Jason S., Sheibani, Nader, Bidkhori, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050429/
https://www.ncbi.nlm.nih.gov/pubmed/30050469
http://dx.doi.org/10.3389/fphys.2018.00907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050429/
https://www.ncbi.nlm.nih.gov/pubmed/30050469
http://dx.doi.org/10.3389/fphys.2018.00907

Ejemplares similares