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Cytoplasmic TrkA Expression as a Screen for Detecting NTRK1 Fusions in Colorectal Cancer()()

NTRK1 gene fusions, the targets of multikinase inhibitors, are promising therapeutic targets for colorectal cancer (CRC). However, screening methods for detecting NTRK1 gene fusions in CRC tissues have not been reported. In this study, we investigated the potential use of immunohistochemistry (IHC)...

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Detalles Bibliográficos
Autores principales: Choi, Yuri, Won, Yeo-Jin, Lee, Sojeong, Kim, Ahrong, Kim, Younggeum, Park, Won-Young, Jo, Hong-Jae, Song, Geun Am, Kwon, Chae Hwa, Park, Do Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050437/
https://www.ncbi.nlm.nih.gov/pubmed/29689458
http://dx.doi.org/10.1016/j.tranon.2018.03.011

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