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Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature
A rare condition in itself, acquired hemophilia A, seldom presents as isolated gross hematuria. It is a serious condition with a high mortality rate and thus clinical suspicion followed by prompt diagnosis is imperative (1). In fact, only 8 cases of such presentation of this condition have been repo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Urologia
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050547/ https://www.ncbi.nlm.nih.gov/pubmed/29144625 http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0172 |
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author | Schmidt-Bowman, Max Reinstatler, Lael Raffin, Eric P. Yared, Joseph E. Seigne, John D. Sverrisson, Einar F. |
author_facet | Schmidt-Bowman, Max Reinstatler, Lael Raffin, Eric P. Yared, Joseph E. Seigne, John D. Sverrisson, Einar F. |
author_sort | Schmidt-Bowman, Max |
collection | PubMed |
description | A rare condition in itself, acquired hemophilia A, seldom presents as isolated gross hematuria. It is a serious condition with a high mortality rate and thus clinical suspicion followed by prompt diagnosis is imperative (1). In fact, only 8 cases of such presentation of this condition have been reported thus far in the literature. Of these, none describe the initial presentation of hematuria with the inciting event of a kidney stone. We present a case of a 67-year-old man with signs and symptoms of nephrolithiasis accompanied by profuse hematuria, who was subsequently found to have developed expression of factor VIII inhibitor leading to acquired hemophilia A. |
format | Online Article Text |
id | pubmed-6050547 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Sociedade Brasileira de Urologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-60505472018-07-18 Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature Schmidt-Bowman, Max Reinstatler, Lael Raffin, Eric P. Yared, Joseph E. Seigne, John D. Sverrisson, Einar F. Int Braz J Urol Challenging Clinical Cases A rare condition in itself, acquired hemophilia A, seldom presents as isolated gross hematuria. It is a serious condition with a high mortality rate and thus clinical suspicion followed by prompt diagnosis is imperative (1). In fact, only 8 cases of such presentation of this condition have been reported thus far in the literature. Of these, none describe the initial presentation of hematuria with the inciting event of a kidney stone. We present a case of a 67-year-old man with signs and symptoms of nephrolithiasis accompanied by profuse hematuria, who was subsequently found to have developed expression of factor VIII inhibitor leading to acquired hemophilia A. Sociedade Brasileira de Urologia 2018 /pmc/articles/PMC6050547/ /pubmed/29144625 http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0172 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Challenging Clinical Cases Schmidt-Bowman, Max Reinstatler, Lael Raffin, Eric P. Yared, Joseph E. Seigne, John D. Sverrisson, Einar F. Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title | Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title_full | Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title_fullStr | Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title_full_unstemmed | Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title_short | Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature |
title_sort | acquired hemophilia presenting as gross hematuria following kidney stone – a case report and review of the literature |
topic | Challenging Clinical Cases |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050547/ https://www.ncbi.nlm.nih.gov/pubmed/29144625 http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0172 |
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