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OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study

PURPOSE: To create a predictive model of involuntary detrusor contraction (IDC) to improve the diagnostic accuracy of overactive detrusor (OAD), associating overactive bladder (OAB) symptoms with other clinical parameters in the female population. MATERIALS AND METHODS: A total of 727 women were stu...

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Autores principales: Arribillaga, Leandro Cristian, Ledesma, Marta, Montedoro, Ariel, Pisano, Florencia, Bengió, Rubén Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050563/
https://www.ncbi.nlm.nih.gov/pubmed/29211399
http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0213
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author Arribillaga, Leandro Cristian
Ledesma, Marta
Montedoro, Ariel
Pisano, Florencia
Bengió, Rubén Guillermo
author_facet Arribillaga, Leandro Cristian
Ledesma, Marta
Montedoro, Ariel
Pisano, Florencia
Bengió, Rubén Guillermo
author_sort Arribillaga, Leandro Cristian
collection PubMed
description PURPOSE: To create a predictive model of involuntary detrusor contraction (IDC) to improve the diagnostic accuracy of overactive detrusor (OAD), associating overactive bladder (OAB) symptoms with other clinical parameters in the female population. MATERIALS AND METHODS: A total of 727 women were studied retrospectively. In all of them, urodynamic study was conducted for urogynecological causes. Demographics information, personal history, symptoms, physical exam, a 3-day frequency/volume chart and urinary culture, were collected in all patients and they subsequently underwent uroflowmetry and urodynamic studies. A logistic regression model was performed in order to determine independent predictors of presence of IDC. Odd ratio (OR) estimation was used to assign a score to each one of the significant variables (p≤0.05) in the logistic regression model. We performed a ROC curve in order to determine the predictive ability of the score in relation to the presence of OAD. RESULTS: presence of OAD was evident in 210 women (29%). In the logistic regression analysis, independent predictors of OAD were urgency, urgency incontinence, nocturia, absence of SUI symptoms, diabetes mellitus, reduction of vaginal trophism and bladder capacity below 150 mL. The probability of IDC diagnosis increases as the score raises (Score 0: 4% until Score ≥10: 88%). Sensitivity was 71% and specificity 72%. The area under the curve of OAB score was 0.784 (p>0.001). CONCLUSIONS: OAB score is a clinical tool that shows higher diagnostic accuracy than OAB symptoms alone to predict overactive detrusor.
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spelling pubmed-60505632018-07-18 OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study Arribillaga, Leandro Cristian Ledesma, Marta Montedoro, Ariel Pisano, Florencia Bengió, Rubén Guillermo Int Braz J Urol Original Article PURPOSE: To create a predictive model of involuntary detrusor contraction (IDC) to improve the diagnostic accuracy of overactive detrusor (OAD), associating overactive bladder (OAB) symptoms with other clinical parameters in the female population. MATERIALS AND METHODS: A total of 727 women were studied retrospectively. In all of them, urodynamic study was conducted for urogynecological causes. Demographics information, personal history, symptoms, physical exam, a 3-day frequency/volume chart and urinary culture, were collected in all patients and they subsequently underwent uroflowmetry and urodynamic studies. A logistic regression model was performed in order to determine independent predictors of presence of IDC. Odd ratio (OR) estimation was used to assign a score to each one of the significant variables (p≤0.05) in the logistic regression model. We performed a ROC curve in order to determine the predictive ability of the score in relation to the presence of OAD. RESULTS: presence of OAD was evident in 210 women (29%). In the logistic regression analysis, independent predictors of OAD were urgency, urgency incontinence, nocturia, absence of SUI symptoms, diabetes mellitus, reduction of vaginal trophism and bladder capacity below 150 mL. The probability of IDC diagnosis increases as the score raises (Score 0: 4% until Score ≥10: 88%). Sensitivity was 71% and specificity 72%. The area under the curve of OAB score was 0.784 (p>0.001). CONCLUSIONS: OAB score is a clinical tool that shows higher diagnostic accuracy than OAB symptoms alone to predict overactive detrusor. Sociedade Brasileira de Urologia 2018 /pmc/articles/PMC6050563/ /pubmed/29211399 http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0213 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Arribillaga, Leandro Cristian
Ledesma, Marta
Montedoro, Ariel
Pisano, Florencia
Bengió, Rubén Guillermo
OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title_full OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title_fullStr OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title_full_unstemmed OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title_short OAB score: A clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
title_sort oab score: a clinical model that predicts the probability of presenting overactive detrusor in the urodynamic study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050563/
https://www.ncbi.nlm.nih.gov/pubmed/29211399
http://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0213
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