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Chiral Brønsted acid-catalyzed intramolecular S(N)2′ reaction for enantioselective construction of a quaternary stereogenic center
An enantioselective intramolecular anti-S(N)2′ cyclization reaction for the construction of a quaternary stereogenic center was accomplished through the activation of the leaving group using a binaphthol-derived phosphoramide as the chiral Brønsted acid catalyst. The present allylic substitution rea...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050593/ https://www.ncbi.nlm.nih.gov/pubmed/30079184 http://dx.doi.org/10.1039/c8sc01942h |