Cargando…

Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders

OBJECTIVE: This study aims at identifying master regulators of transcriptional networks in autism spectrum disorders (ASDs). RESULTS: With two sets of independent RNA-Seq data generated on cerebellum from patients with ASDs and control subjects (N = 39 and 45 for set 1, N = 24 and 38 for set 2, resp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doostparast Torshizi, Abolfazl, Duan, Jubao, Wang, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050725/ https://www.ncbi.nlm.nih.gov/pubmed/30016992 http://dx.doi.org/10.1186/s13104-018-3594-0

Ejemplares similares

A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2021)

Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2022)

Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2020)

Deconvolution of Transcriptional Networks in Post-Traumatic Stress Disorder Uncovers Master Regulators Driving Innate Immune System Function
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2017)

Cell Type-Specific Annotation and Fine Mapping of Variants Associated With Brain Disorders
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2020)

Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
por: Doostparast Torshizi, Abolfazl, et al.
Publicado: (2019)

Integrated analysis on transcriptome and behaviors defines HTT repeat-dependent network modules in Huntington's disease
por: Huang, Lulin, et al.
Publicado: (2021)

Retraction Note: PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression
por: Benjamins, René, et al.
Publicado: (2021)

Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
por: Loveday, Chey, et al.
Publicado: (2015)

Corrigendum: Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
por: Loveday, Chey, et al.
Publicado: (2019)

Reduced sensitivity to minimum-jerk biological motion in autism spectrum conditions
por: Cook, Jennifer, et al.
Publicado: (2009)

Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B
por: Krzyzosiak, Agnieszka, et al.
Publicado: (2018)

Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR
por: Saldanha, Paulo André, et al.
Publicado: (2022)

Occupational performance of children with autism spectrum disorder and quality of life of their mothers
por: Beheshti, Seyedeh Zeinab, et al.
Publicado: (2022)

S289: PPP1R1B BINDS IRON REGULATORY PROTEINS AND MODULATES IRON CELLULAR CONTENT
por: Calvo López, Laura, et al.
Publicado: (2023)

Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer
por: Xie, Wenjun, et al.
Publicado: (2021)

Differential pattern of glycogen accumulation after protein phosphatase 1 glycogen-targeting subunit PPP1R6 overexpression, compared to PPP1R3C and PPP1R3A, in skeletal muscle cells
por: Montori-Grau, Marta, et al.
Publicado: (2011)

A system for generating transcription regulatory networks with combinatorial control of transcription
por: Roy, Sushmita, et al.
Publicado: (2008)

The broad phenotypic spectrum of PPP2R1A-related neurodevelopmental disorders correlates with the degree of biochemical dysfunction
por: Lenaerts, Lisa, et al.
Publicado: (2020)

Retraction Note to: Vitamin A deficiency and sleep disturbances related to autism symptoms in children with autism spectrum disorder: a cross-sectional study
por: Wen, Jing, et al.
Publicado: (2021)

The germline-enriched Ppp1r36 promotes autophagy
por: Zhang, Qinghua, et al.
Publicado: (2016)

STREAM: Static Thermodynamic REgulAtory Model of transcription
por: Bauer, Denis C., et al.
Publicado: (2008)

Epistatic evidence for gender-dependant slow neurotransmission signalling in substance use disorders: PPP1R12B versus PPP1R1B
por: Liu, Kefu, et al.
Publicado: (2020)

Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons
por: Huang, Guanqun, et al.
Publicado: (2019)

PPP1R81 correlates with the survival and cell proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders
por: Huang, Tzyy-Nan, et al.
Publicado: (2015)

Improving GNSS PPP Convergence: The Case of Atmospheric-Constrained, Multi-GNSS PPP-AR
por: Aggrey, John, et al.
Publicado: (2019)

Estimating gene regulatory networks with pandaR
por: Schlauch, Daniel, et al.
Publicado: (2017)

Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation
por: Salter, E. Alan, et al.
Publicado: (2023)

Expression and distribution of PPP2R5C gene in leukemia
por: Zheng, Haitao, et al.
Publicado: (2011)

Dysfunctions in brain networks supporting empathy: An fMRI study in adults with autism spectrum disorders
por: Schulte-Rüther, Martin, et al.
Publicado: (2010)

Abnormal Activation of the Social Brain Network in Children with Autism Spectrum Disorder: An fMRI Study
por: Kim, Sun-Young, et al.
Publicado: (2015)

Brain activity for spontaneous and explicit mentalizing in adults with autism spectrum disorder: An fMRI study
por: Nijhof, Annabel D., et al.
Publicado: (2018)

PP2A subunit PPP2R2C is downregulated in the brains of Alzheimer’s transgenic mice
por: Leong, Waiian, et al.
Publicado: (2020)

PS: 10$^{13}$ ppp
Publicado: (1975)

Broad-spectrum XX and XY gonadal dysgenesis in patients with a homozygous L193S variant in PPP2R3C
por: Cicek, Dilek, et al.
Publicado: (2021)

Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure
por: Grimm, P. Richard, et al.
Publicado: (2023)

Autism cornered: network analyses reveal mechanisms of autism spectrum disorders
por: Auffray, Charles
Publicado: (2014)

Eukaryotic-like phosphoprotein phosphatase (PPP) enzyme evolution: interactions with environmental toxins and regulatory proteins
por: Kerk, David, et al.
Publicado: (2023)

Identification of Natural Antisense Transcripts in Mouse Brain and Their Association With Autism Spectrum Disorder Risk Genes
por: Koç, Baran, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p8t5t7ra4gvn1u8sa8adfcg090