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Thrombopoietin knock-in augments platelet generation from human embryonic stem cells
BACKGROUND: Refinement of therapeutic-scale platelet production in vitro will provide a new source for transfusion in patients undergoing chemotherapy or radiotherapy. However, procedures for cost-effective and scalable platelet generation remain to be established. METHODS: In this study, we establi...
Autores principales: | Zhang, Leisheng, Liu, Cuicui, Wang, Hongtao, Wu, Dan, Su, Pei, Wang, Mengge, Guo, Jiaojiao, Zhao, Shixuan, Dong, Shuxu, Zhou, Wen, Arakaki, Cameron, Zhang, Xiaobing, Zhou, Jiaxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050740/ https://www.ncbi.nlm.nih.gov/pubmed/30016991 http://dx.doi.org/10.1186/s13287-018-0926-x |
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