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Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages

Macrophages are critical to innate immunity due to their ability to phagocytose bacteria. The macrophage phagolysosome is a highly acidic organelle with potent antimicrobial properties, yet remarkably, ingested Staphylococcus aureus replicates within this niche. Herein we demonstrate that S. aureus...

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Detalles Bibliográficos
Autores principales:	Flannagan, Ronald S., Kuiack, Robert C., McGavin, Martin J., Heinrichs, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050959/ https://www.ncbi.nlm.nih.gov/pubmed/30018109 http://dx.doi.org/10.1128/mBio.01143-18

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