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Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder

INTRODUCTION: Cognitive disorders are a clinical and research challenge; in particular, the mild cognitive disorder (MiCD) requires diagnostic suspicion and tools with adequate performance for its detection. The objective of this study was the validation of a short cognitive test (CATest) for the de...

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Autores principales: Estrada-Orozco, Kelly, Bonilla-Vargas, Kely, Cruz, Francy, Mancera, Oscar, Ruiz, Miguel, Alvarez, Laura, Pardo, Rodrigo, Arboleda, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051079/
https://www.ncbi.nlm.nih.gov/pubmed/30057805
http://dx.doi.org/10.1155/2018/3280621
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author Estrada-Orozco, Kelly
Bonilla-Vargas, Kely
Cruz, Francy
Mancera, Oscar
Ruiz, Miguel
Alvarez, Laura
Pardo, Rodrigo
Arboleda, Humberto
author_facet Estrada-Orozco, Kelly
Bonilla-Vargas, Kely
Cruz, Francy
Mancera, Oscar
Ruiz, Miguel
Alvarez, Laura
Pardo, Rodrigo
Arboleda, Humberto
author_sort Estrada-Orozco, Kelly
collection PubMed
description INTRODUCTION: Cognitive disorders are a clinical and research challenge; in particular, the mild cognitive disorder (MiCD) requires diagnostic suspicion and tools with adequate performance for its detection. The objective of this study was the validation of a short cognitive test (CATest) for the detection of MiCD in population of 50 years or more. METHODS: A diagnostic accuracy study was assembled and performed in a prospective cohort. A consecutive sample of 200 Colombian subjects who represented the whole spectrum of the condition of interest allowed us to reach the objective. Validity was determined by concurrent criteria. The cut points were determined by the ROC curves considering the best overall performance and accuracy of the test. RESULTS: CATest was validated to detection of MiCD at a cut-off point of 18. As a result, scores lower than 18 classified the participants as MiCD. At this cut-off point, CATest showed sensitivity of 84.3% (CI 76 to 90.16), specificity of 71.4% (CI 95% 61.8 to 79.43), positive predictive value of 75% ( 95% CI 66.79 to 82.42), and area under curve AUC 0.8518 (standard error SE 0.0265). DISCUSSION: CATest has an adequate performance as a short cognitive test for the detection of MiCD. Its performance is superior to MiniMental and similar to Montreal Cognitive test (MoCA) according to the data reported in the literature. The advantages over other tests are the evaluation of all cognitive domains, time of application, and easy interpretation of results. CATest is a free use alternative for MiCD detection.
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spelling pubmed-60510792018-07-29 Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder Estrada-Orozco, Kelly Bonilla-Vargas, Kely Cruz, Francy Mancera, Oscar Ruiz, Miguel Alvarez, Laura Pardo, Rodrigo Arboleda, Humberto Int J Alzheimers Dis Research Article INTRODUCTION: Cognitive disorders are a clinical and research challenge; in particular, the mild cognitive disorder (MiCD) requires diagnostic suspicion and tools with adequate performance for its detection. The objective of this study was the validation of a short cognitive test (CATest) for the detection of MiCD in population of 50 years or more. METHODS: A diagnostic accuracy study was assembled and performed in a prospective cohort. A consecutive sample of 200 Colombian subjects who represented the whole spectrum of the condition of interest allowed us to reach the objective. Validity was determined by concurrent criteria. The cut points were determined by the ROC curves considering the best overall performance and accuracy of the test. RESULTS: CATest was validated to detection of MiCD at a cut-off point of 18. As a result, scores lower than 18 classified the participants as MiCD. At this cut-off point, CATest showed sensitivity of 84.3% (CI 76 to 90.16), specificity of 71.4% (CI 95% 61.8 to 79.43), positive predictive value of 75% ( 95% CI 66.79 to 82.42), and area under curve AUC 0.8518 (standard error SE 0.0265). DISCUSSION: CATest has an adequate performance as a short cognitive test for the detection of MiCD. Its performance is superior to MiniMental and similar to Montreal Cognitive test (MoCA) according to the data reported in the literature. The advantages over other tests are the evaluation of all cognitive domains, time of application, and easy interpretation of results. CATest is a free use alternative for MiCD detection. Hindawi 2018-07-02 /pmc/articles/PMC6051079/ /pubmed/30057805 http://dx.doi.org/10.1155/2018/3280621 Text en Copyright © 2018 Kelly Estrada-Orozco et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Estrada-Orozco, Kelly
Bonilla-Vargas, Kely
Cruz, Francy
Mancera, Oscar
Ruiz, Miguel
Alvarez, Laura
Pardo, Rodrigo
Arboleda, Humberto
Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title_full Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title_fullStr Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title_full_unstemmed Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title_short Cognitive Assessment Test: Validation of a Short Cognitive Test for the Detection of Mild Cognitive Disorder
title_sort cognitive assessment test: validation of a short cognitive test for the detection of mild cognitive disorder
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051079/
https://www.ncbi.nlm.nih.gov/pubmed/30057805
http://dx.doi.org/10.1155/2018/3280621
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