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Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress

AIM: Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity. We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO-1) levels in adipose and hepatic tissue, result...

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Detalles Bibliográficos
Autores principales: Sacerdoti, David, Singh, Shailendra P., Schragenheim, Joseph, Bellner, Lars, Vanella, Luca, Raffaele, Marco, Meissner, Aliza, Grant, Ilana, Favero, Gaia, Rezzani, Rita, Rodella, Luigi F., Bamshad, David, Lebovics, Edward, Abraham, Nader G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051135/
https://www.ncbi.nlm.nih.gov/pubmed/30057822
http://dx.doi.org/10.1155/2018/3484107