Downregulation of AGR2, p21, and cyclin D and alterations in p53 function were associated with tumor progression and chemotherapy resistance in epithelial ovarian carcinoma

Anterior gradient 2 protein belongs to a family of chaperone‐like proteins, namely protein disulfide isomerase. Generally, AGR2 is highly expressed in mucus‐secreting cells and endocrine organs, and in this study, we aimed to evaluate AGR2 and cell cycle molecules in epithelial ovarian cancer and it...

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Detalles Bibliográficos
Autores principales: Alves, Mariana Rezende, e Melo, Natalia Cruz, Barros‐Filho, Mateus Camargo, do Amaral, Nayra Soares, Silva, Felipe Ilelis de Barros, Baiocchi Neto, Glauco, Soares, Fernando Augusto, de Brot Andrade, Louise, Rocha, Rafael Malagoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051166/
https://www.ncbi.nlm.nih.gov/pubmed/29845750
http://dx.doi.org/10.1002/cam4.1530

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